Promethazine-dm Coupons & Discount Card – Guaranteed Prices from $2.00

Promethazine DM is a medication that requires careful consideration due to its potential risks and the specific precautions needed for its use. Below is a summary of the key safety information and warnings associated with this drug.

• Respiratory Depression: Promethazine DM can cause significant slowing of breathing, which can be life-threatening, especially in children under 2 years old. Those with existing breathing issues or taking other medications that may depress breathing (e.g., opioids) should use the lowest effective dose for the shortest time necessary. Immediate medical attention is required if you notice slow or shallow breathing.

• Excessive Drowsiness: This medication can cause marked drowsiness, which is exacerbated by alcohol or other sedatives, such as opioids or sleep aids. Avoid activities requiring full alertness, such as driving, until the effects of the medication are known. Seek medical help if you experience severe drowsiness or symptoms like slurred speech or dizziness.

• Neuroleptic Malignant Syndrome (NMS): Although rare, NMS is a serious condition that can occur with promethazine DM, particularly in those taking antipsychotic medications. Symptoms include high fever, rapid heartbeat, stiff muscles, and confusion. Discontinue use and seek urgent medical care if these symptoms appear.

• Uncontrolled Muscle Movements: Promethazine can lead to involuntary movements, such as tongue thrusting or neck twisting, particularly in children who are sick and dehydrated or in those taking MAOIs. Report these symptoms to your healthcare provider immediately.

• Seizure Risk: Those with a history of seizures or taking medications like tramadol that lower the seizure threshold may experience more frequent seizures with promethazine DM. Immediate medical attention is advised if you experience symptoms such as uncontrolled movements or tingling.

• Infection Risk: A decrease in white blood cells can occur, increasing infection susceptibility, especially for those undergoing chemotherapy. Symptoms like fever or chills should be reported to a healthcare provider promptly.

• Overdose Risk: Dextromethorphan, an active ingredient, is found in many over-the-counter products. Using multiple products with dextromethorphan can lead to overdose. Be cautious of combining with other cough, flu, or allergy medications.

Contraindications: Promethazine DM should not be used in children under 2 years, individuals currently on MAOIs, those in a coma, or for treating lower respiratory tract conditions like asthma or COPD. Always consult your healthcare provider to ensure this medication is safe for your specific condition.

Common side effects:

• drowsiness
• dizziness
• blurred vision
• nausea
• constipation
• dry mouth

Less common but important to monitor:

• decreased coordination
• difficulty urinating
• shaking or tremors
• mental or mood changes
• nervousness
• excitement
• irritability
• confusion
• hallucinations
• abnormal or uncontrolled movements
• slow heartbeat
• fainting
• slow or shallow breathing
• seizures

Serious side effects:

• neuroleptic malignant syndrome (NMS)
• allergic reactions
• rash
• itching
• swelling
• severe dizziness
• trouble breathing

Interactions with high risk of serious adverse effects and should be avoided:

• MAO inhibitors (such as isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine)

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Opioid pain or cough medications (such as codeine, hydrocodone)
• Alcohol
• Marijuana (cannabis)
• Drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem)
• Muscle relaxants (such as carisoprodol, cyclobenzaprine)
• Other antihistamines (such as cetirizine, diphenhydramine)

Interactions with low risk that usually do not require a change in therapy:

• Topical antihistamines (such as diphenhydramine in anti-itch creams, ointments, sprays)
• Metoclopramide
• Rolapitant